![]() Yet, there is limited computer-software to assist scientists in this task. ![]() Moreover, the scientific literature describes the mathematics of power analyses for a variety of specialized experimental designs. The principals for power calculation can be found in standard statistical textbooks. Thus, it is an indispensable procedure both for a priori and a posteriori analyses in genetic association studies. Alternatively, power analysis can be used to explore possible reasons for equivocal or negative results. Indeed, most grants applications for genetic association studies require a power analysis section to justify the research proposal. Power calculations elucidates the actual sample size needed to find a true genotype-phenotype correlation under the study constraints. ![]() Statistical power analyses constitute a key step in the design process of these studies. Case-control genetic association studies are increasingly being used in studying the genetic basis of human complex traits.
0 Comments
Leave a Reply. |